Atomic force microscopy of gastric mucin and chitosan mucoadhesive systems

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Atomic force microscopy of gastric mucin and chitosan mucoadhesive systems.

Atomic force microscopy has been utilized to probe, at a molecular level, the interaction between purified pig gastric mucin (PGM) and a mucoadhesive cationic polymer, chitosan (sea cure 210+), with a low degree (approx. 11%) of acetylation. Images were produced detailing the structures of both PGM and chitosan in 0.1 M acetate buffer (pH 4.5), followed by the complex of the two structures in t...

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ژورنال

عنوان ژورنال: Biochemical Journal

سال: 2000

ISSN: 0264-6021,1470-8728

DOI: 10.1042/bj3480557